The medication
nonadherence epidemic

The World Health Organization notes that on average 50% of those suffering from chronic illnesses like diabetes and hypertension do not adhere to their medication therapies. This is despite the severity of the potential consequences of non-adherence, including worsening condition, increased costs and even death.



Even when experiencing symptoms, more than 50% of patients could not achieve the desired level of inhaled corticosteroid use. 4


Poor adherence to preventative asthma therapies leads to poor clinical outcomes, such as asthma exacerbations, resulting in increased hospitalisation and emergency department visits and the associated financial costs. 5


Low cost interventions that improve adherence have been consistently shown to improve outcomes and save money 6

  • Use of the Hailie™ solution (previously known as SmartinhalerTM platform) improved adherence to preventative medication by 180% and reduced use of reliever medication by 45% in a study of 220 children who were monitored over a 6 month period. Chan concluded the use of an audio-visual reminder inhaler can lead to significant improvements in medication adherence and asthma control in school-aged children with asthma.

    Chan et al. Lancet Respir Med. 2015;3:210-219.

Clinical literature & References

  1. Weinstein AG. The potential of asthma adherence management to enhance asthma guidelines. Ann Allergy Asthma Immunol. 2011;106:283-291.
  2. Ingerski LM, Hente EA, Modi AC, Hommel KA. Electronic measurement of medication adherence in pediatric chronic illness: A review of measures. J Pediatr. 2011;159(4):528-534.
  3. Boulet LP, Vervloet D, Magar Y, Foster JM. Adherence: The Goal to Control Asthma. Clin Chest Med. 2012;33:405-417.
  4. Pritchard JN, Nikander K. Impact of intervention and feedback on adherence to treatment. Respiratory Drug Delivery 2012;271-282.
  5. Chan AH, Reddel HK, Apter A, Eakin M, Riekert K, Foster JM. Adherence monitoring and e-health: How clinicians and researchers can use technology to promote inhaler adherence for asthma. J Allergy Clin Immunol Pract. 2013;1(5):446-454.
  6. Morton RW, Everard ML, Elphick HE. Adherence in childhood asthma: the elephant in the room. Arch Dis Child. 2014. Downloaded from 02 June 2014 as 10.1136/archdischild-2014-306243.
  7. Howard S, Lang A, Patel M, Sharples S, Shaw D. Electronic monitoring of adherence to inhaled medication in asthma. Current Respiratory Medicine Reviews. 2014;10:50-63.
  8. Chan AH, Harrison J, Black PN, Mitchell EA, Foster JM. Using electronic monitoring devices to measure inhaler adherence: A practical guide for clinicians. J Allergy Clin Immunol Pract 2015;3:335-49.
  9. Chan AHY, Stewart AWS, Harrison J, Camargo C, Black PN, Mitchell EA. The effect of an inhaler with ringtones on asthma control and school attendance in children. Lancet Respir Med. 2015;3:210-219